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Updated: Sep 13, 2025

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
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在基切除修复中MYC的功能可以保护RAS诱导的衰老

Camila C F Faraco1,2, Wanting Zhu1,3, Anne-Marie Fortier1

  • 1Goodman Cancer Institute, McGill University, Montreal, H3A 1A3, Quebec, Canada.

Nucleic acids research
|July 30, 2025
PubMed
概括

MYC瘤基因通过与DNA聚合酶β相互作用来防止癌细胞衰老,以增强DNA修复. 这种机制对于MYC-RAS在推动瘤发展方面的合作至关重要.

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