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Updated: Jul 6, 2026

Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells
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人类胰腺小岛的综合性单细胞多基因分析识别了与T1D相关的基因和调控信号

Ricardo D'Oliveira Albanus1, Xiaoshan Zhang2, Zeping Zhao2

  • 1Gilbert S. Omenn Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.

Cell reports
|July 30, 2025
PubMed
概括

这项研究整合了多原子数据,以精确确定胰腺β细胞中与1型糖尿病 (T1D) 风险信号相关的基因和调控元素. 它确定了增加β细胞脆弱性的特定遗传变异,为T1D提供了新的机制性见解.

关键词:
科普:基因组学 基因组学CP:新陈代谢过程中的新陈代谢.在GWAS中,GWAS就是GWAS.与T1D相关的信号灭症 (apoptosis) 是一种死亡的过程.细胞因子细胞因子不同化的差异化差异化.hPSCs是什么意思人类胰腺小岛多个主题的个人资料.第1类糖尿病 1型糖尿病的β细胞是β细胞.

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