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相关概念视频

Self-Evaluation: Self-Enhancement and Self-Verification03:00

Self-Evaluation: Self-Enhancement and Self-Verification

Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
Multiple Comparison Tests01:13

Multiple Comparison Tests

Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Randomized Experiments01:13

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The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
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基于机器学习的认知评估与自主认知检查:随机对照试验

Calvin Howard1,2,3,4, Amy Johnson5, Sheena Baratono1,2

  • 1Center for Brain Circuit Therapeutics, Brigham & Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA, 02215, United States.

Journal of medical Internet research
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PubMed
概括

自主认知检查 (ACoE) 可靠地评估认知功能,并可以选患者,类似于传统测试. 这个数字工具为临床环境中的认知表型提供了一个可扩展的解决方案.

关键词:
一个ACoEE一个ACoEML ML ML 在这里.关注注意力注意力注意力注意力自主认知检查自主认知检查认知 认知 认知认知评估是一种认知评估.认知检查 认知检查 认知检查认知测试是一种认知测试.痴呆症 痴呆症是一种痴呆症.流动性的流性语言语言语言语言语言语言.机器学习是机器学习.记忆 记忆 记忆 记忆 记忆神经学 神经学 神经学神经心理学神经心理学视觉空间的功能.

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科学领域:

  • 神经学 神经学
  • 认知科学 认知科学
  • 数字健康数字健康

背景情况:

  • 痴呆症患病率上升需要可扩展的认知评估解决方案.
  • 自主认知检查 (ACoE) 是认知症状表型化的基础工具.
  • 目前尚不清楚ACoE在临床人群中的外部验证及其查实用性.

研究的目的:

  • 为了外部验证自主认知检查 (ACoE) 以获得可靠的认知表型.
  • 与标准的纸质认知测试相比,评估ACOE作为选工具的有效性.

主要方法:

  • 一项随机交叉研究涉及46名神经病患者,将ACoE与纸质测试 (ACE-3或MoCA) 进行比较.
  • 评估了整体和特定领域认知得分的评分器间可靠性.
  • 评估了ACOE与已建立的认知评估相似地对患者进行分类的能力.

主要成果:

  • 对于整体认知分数 (ICC=0.89) 和特定领域 (注意:ICC=0.74,语言:ICC=0.89,记忆:ICC=0.91,流利性:ICC=0.74,视觉空间:ICC=0.78) 的评级者间可靠性是很高的.
  • ACoE有效地选患者,实现与纸质测试具有很高的诊断相似性 (AUC=0.96).

结论:

  • 自主认知检查 (ACoE) 可靠地确定患者认知症状的表型.
  • ACoE对于查认知障碍患者是有效的.
  • 未来的应用可能包括诊断特定的认知病因.