新生儿实践的变化和支气管肺形的时间趋势
Georgina Dickenson1, Oishi Sikdar2, Ravi Bhat2
1King's College London, London, United Kingdom.
American journal of perinatology
|July 30, 2025
概括
2012-2014年至2020-2022年期间,支气管肺功能障碍症 (BPD) 增加,与更多的早产和生长受限制的婴儿有关. 增加皮和利尿剂的使用并没有改善结果.
科学领域:
- 新生儿医学 新生儿医学
- 儿科肺病学 儿科肺病学
- 产周研究 产周研究
背景情况:
- 支气管肺功能障碍症 (BPD) 是新生儿重症监护中的重大并发症,发病率越来越高.
- 了解BPD的时间趋势对于评估不断变化的新生儿护理实践至关重要.
研究的目的:
- 调查新生儿护理实践的变化与BPD发病率的时间趋势之间的联系.
- 在怀孕32周以下的婴儿中比较BPD结果,跨越两个不同的时间段:2012-2014和2020-2022.
主要方法:
- 追溯队列研究,比较两个时期 (2012-2014年和2020-2022年) 怀孕32周以下的婴儿.
- 从患者记录和BadgerNet电子系统中提取的数据.
- 结果按妊娠年龄分层 (<28周和28-32周).
主要成果:
- 最近的时代 (2020-2022) 包含了更多的不成熟婴儿 (更低的妊娠年龄,更高的妊娠年龄小的比例).
- 在最近的时代中,中度/重度BPD的发病率显著增加 (64%对39%,p<0.001).
- 最近,人们观察到皮,利尿剂,,以及较少侵入性表面活性剂的使用增加,但没有改善结果或更晚的出院.
结论:
- 随着BPD发病率的上升,早产和生长限制的增加也随之增加.
- 在新生儿护理中扩大使用皮和利尿剂与更好的BPD结局无关.
- 需要进一步的研究,以确定有效的策略,以减轻脆弱的新生儿BPD.
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