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在怀疑低皮质皮质症的狗体内临床皮质醇试验的诊断性能

Ana Torrano Guillamón¹, Casandra Juárez Sarrión¹, Eva Prosper Asensi¹

¹AniCura Valencia Sur Veterinary Hospital, Valencia, Spain.

American journal of veterinary research

|July 30, 2025

概括

IDEXX SNAP测试可以准确检测狗的低上皮质 (HA),与兽医参考实验室的相关性很好. 虽然通常可靠,但边界结果需要确认以确定HA诊断.

科学领域:

兽医诊断兽医诊断兽医诊断兽医诊断
内分泌学在内分泌学.
照顾点检测检测照顾点检测

背景情况:

低皮皮质性 (HA) 是一种严重的犬内分泌疾病.
准确和快速的诊断对于及时治疗至关重要.
现有的诊断方法可能会耗时.

研究的目的:

为了评估 IDEXX SNAP ELISA 测试对狗的低上皮质症的诊断准确性.
评估SNAP测试与兽医参考实验室 (VRL) 之间的协议,以测量皮质醇.
确定SNAP测试在帮助HA诊断中的有用性.

主要方法:

预期观察性诊断准确性研究 (2023年1月 - 2024年1月).
注册的狗可疑患有低 adrenocorticism. 这是一只可疑的狗.
将IDEXX SNAP ELISA结果与VRL化学发光免疫测试 (IMMULITE 2000) 皮质醇测量结果进行比较,使用ACTH刺激测试作为黄金标准.

主要成果:

招募了96只狗;21只被诊断患有HA. 在SNAP和VRL之间存在很强的相关性 (斯皮尔曼 ρ = 0.923,P < .001).
对于基底血清皮质醇<2μg/dL,SNAP的特异性 (73.1%) 比VRL (64.2%) 更高.
SNAP对ACTH后皮质醇<2μg/dL显示95.2%的敏感性.

结论:

IDEXX SNAP测试显示了与VRL在诊断HA的良好相关性.
SNAP 基础血清皮质醇可能提供更高的特异性来排除HA.
边界线后ACTH SNAP结果需要由VRL确认.

关键词:

艾丽莎·伊丽莎·伊丽莎这是一个SNAP测试.狗类的阴腺皮质过低.皮质醇免疫检测试验皮质醇免疫检测试验皮质上腺下降症 (hypoadrenocorticism) 是一种疾病.

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