视网膜和冠状腺血管疾病的病毒载体的眼部传递:一篇评论
Rajat Agrawal1, Sydney V Oraskovich2, Peter Francis1
1From Ray Therapeutics, Inc., Berkeley, California, USA (R.A., P.F.).
American journal of ophthalmology
|July 30, 2025
概括
基因疗法为视网膜血管疾病提供了一个有前途的单次注射治疗方法,利用腺相关病毒 (AAV) 载体. 本综述探讨了基于AAV的疗法,输送方法和这些重大眼部疾病的临床进展.
科学领域:
- 眼科医生 眼科 眼科
- 血管生物学 血管生物学
- 基因治疗 基因治疗
背景情况:
- 视网膜和胸腔血管疾病是一个全球性的健康挑战,其特点是新血管化和.
- 目前的治疗方法涉及昂贵的,反复注射抗血管原性疗法.
- 基因疗法,特别是使用腺相关病毒 (AAV) 载体,正在成为一种安全的,单次注射的替代方案.
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