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在随机对照试验中偏好行为改变策略:来自体重管理的证据
Michael Sobolev1, Julissa Ruiz2, Márcio A Diniz3
1Cedars-Sinai Medical Center, Los Angeles, CA, United States of America; University of Southern California, Los Angeles, CA, United States of America.
Contemporary clinical trials
|July 30, 2025
概括
体重管理试验中近40%的参与者表示他们更喜欢特定的研究组,即使愿意随机选择. 了解这种偏好是改善试验保留和结果的关键.
科学领域:
- 行为科学 行为科学
- 临床试验 临床试验
- 重量管理重量管理
背景情况:
- 参与者对研究臂的偏好可以影响试验招生和持续时间.
- 了解参与者的偏好对于有效的临床试验设计至关重要.
- 避免/抵抗试验研究了在体重管理中弥合意图-行为差距的策略.
研究的目的:
- 评估参与者对两种不同的体重管理策略的偏好:避免 (厨房改装,在线杂货) 和抵抗 (抑制性控制培训).
- 在随机化之前,根据参与者的喜好和对干预策略的感知益处来确定参与者的集群.
主要方法:
- 采用选过程,参与者对策略的情感价值和工具效用进行评分.
- 雇佣K-意味着根据个人偏好对个人进行集群.
- 收集了2024年1月至2025年1月期间306名参与者的数据.
主要成果:
- 对于这两种策略,在喜欢和感知好处等级之间观察到很高的相关性 (>0.70).
- "避免"和"抵抗"两种策略在喜欢和感知到的好处方面均获得了高的中位数.
- 三个不同的偏好集群出现了:对两者都非常有利 (61%),对抵抗的偏好 (22%) 和对避免的偏好 (17%).
结论:
- 很大一部分人 (近40%) 表现出对某一特定组的相对偏好,即使在随机化时也如此.
- 需要进一步的研究,以阐明相对偏好对体重控制试验的保留,坚持和结果的影响.
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