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卡米尔2缺乏会破坏T细胞中激活诱导的代谢重编程,并通过补充谷氨胺来部分挽救

Mona Kabha1, Maya Liaks-Bohnick2, Fadia Zagairy3

  • 1Faculty of Biology, Technion Israel Institute of Technology, Haifa, Israel.

The Journal of allergy and clinical immunology
|July 30, 2025
PubMed
概括

卡米尔2缺乏会损害T细胞代谢,尤其是谷氨胺通路. 补充谷氨酸在患有CARMIL2突变的患者中部分恢复了免疫细胞功能和激活标志物.

关键词:
卡米尔2 卡米尔2一个T细胞细胞.谷氨胺是一种在mTOROR中使用mTOR.代谢 代谢 代谢 代谢

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