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ShH10病毒载体用于内耳支细胞的安全,高效和选择性转导

Yun Ji Bertken1, Yeeun Kim2, Juan Llamas2

  • 1Keck School of Medicine of University of Southern California, 1975 Zonal Ave, Los Angeles, CA 90033, USA.

Developmental biology
|July 30, 2025
PubMed
概括

一种新的腺相关病毒 (AAV) 血清型,ShH10,有效地向内耳的支持细胞进行基因治疗. 这一发现为治疗感官神经听力损失提供了一个有前途的新途径,而不会扩散到中枢神经系统.

关键词:
在 AAV AAV AAV 中.格利亚·格利亚是什么?头发细胞是指头发的细胞.助听器 助听器 助听器内耳基因疗法是内耳的基因治疗.感官上皮质感觉上皮质感觉上皮质支持细胞 支持细胞

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