患有急性心力衰竭的患者 Delirium 的危险因素:系统性审查和元分析
Tetsushi Kawazoe1, Tomoaki Ishida2, Kohei Jobu3
1Center for Clinical Pharmacy Education and Research, School of Pharmaceutical Sciences, Mukogawa Women's University, 11-68 Koshien-Kuban-cho, Nishinomiya, Hyogo 663-8179, Japan.
Biological & pharmaceutical bulletin
|July 30, 2025
概括
这次元分析确定了急性心力衰竭 (AHF) 患者妄的14个风险因素. 识别这些因素可以帮助临床医生预测和预防高风险个体的妄想.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 临界护理医学 临界护理医学
背景情况:
- 妄想是一种急性,危及生命的疾病,影响注意力,思维和意识.
- 患有急性心力衰竭 (AHF) 的住院患者经常经历妄想.
- 在AHF患者中早期识别妄风险因素对于及时干预至关重要.
研究的目的:
- 进行元分析,确定AHF (AHF-D) 住院患者痴呆症的风险因素.
- 综合来自原始研究的证据,以建立AHF-D风险因素的全面清单.
主要方法:
- 在PubMed,Scopus,Ichushi和Cochrane图书馆数据库中进行系统搜索.
- 包括6项符合条件的研究,包括3867名AHF患者,其中796人患有妄想.
- 数据的提取,包括研究设计,妄想评估和统计测量 (OR,SMD).
主要成果:
- 在AHF患者中确定了14个神经失调的显著风险因素.
- 关键的危险因素包括老年,低BMI,机械通风,并发病 (中风,痴呆,抑郁症),特定药物 (抗精神病药物,二氨酸药物) 和异常的实验室值 (高HR,BNP,BUN,肌素;低白蛋白,).
结论:
- 该研究成功地确定了许多与AHF妄相关的危险因素.
- 这些发现为临床医生提供了宝贵的见解,帮助他们主动识别和管理患有 Delirium 高风险的患者.
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