在营养风险癌症患者中,FSMP对营养状况和肉症的影响:一项随机,双盲,安慰剂控制的随机研究
1Department of Clinical Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Asia Pacific journal of clinical nutrition
|July 30, 2025
概括
特殊医疗用途食品 (FSMP) 改善了癌症患者的营养状况和身体表现. 这种营养支持降低了营养风险,增强了肌肉质量,使瘤门诊患者受益.
科学领域:
- 在瘤学瘤学.
- 临床营养学 临床营养学
- 老年病的医生 老年病的医生
背景情况:
- 营养风险会对癌症患者的预后产生负面影响.
- 营养支持可以改善风险癌症患者的结果.
- 特殊医疗用途食品 (FSMP) 需要进一步评估瘤学中的安全性和有效性.
研究的目的:
- 评估FSMP对癌症门诊患者营养状况和肉症的影响.
- 评估运动表现,肌肉质量和炎症标志物的变化.
- 为了确定FSMP在改善营养风险得分方面的有效性.
主要方法:
- 单中心,双盲,随机对照的干预研究.
- 在营养风险癌症患者中,使用FSMP或控制剂进行8周的口服干预.
- 评估营养风险 (NRS2002),身体表现,肌肉质量和炎症因素.
主要成果:
- 与对照组相比,FSMP显著降低了营养风险患者的百分比.
- 在Timed Up和Go测试中观察到的改善,步行速度,握力和上肢肌肉质量.
- 萨尔科佩尼亚患病率,小腿周长,hsCRP或25(OH) VD3水平没有显著变化.
结论:
- FSMP有效改善癌症患者的营养状况.
- 在这个人群中,FSMP提高了身体表现和上肢肌肉质量.
- 可能需要进一步的研究,以解决sarcopenia的患病率和特定的炎症标志物.
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