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Updated: Sep 13, 2025

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors
07:51

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors

Published on: November 14, 2014

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细胞自主性GABAARs对于NMDAR介导的突触传输,LTP和空间记忆至关重要

Jing-Jing Duan1,2,3, Bin Jiang4, Wei Yin5

  • 1Department of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, China. duanjj2@mail.sysu.edu.cn.

EMBO reports
|July 30, 2025
PubMed
概括

这项研究揭示了GABAA受体 (GABAARs) 对大脑中的NMDAR功能,突触可塑性和空间记忆至关重要. 沉默GABAARs会损害这些功能,强调它们的调节作用.

关键词:
在 E/I 余额中.在 GABAARs 的研究中,GABAARs 是在 LTP LTP 中.没有NMDAR的药物.空间记忆 空间记忆

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