Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

541
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
541
Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

202
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
202
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

162
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
162
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

1.0K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.0K
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

128
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
128

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Immunoglobulin κ drives liver regeneration by stabilizing MYLK to maintain cytoskeletal integrity and promote hepatocyte proliferation.

Journal of translational internal medicine·2026
Same author

Comparative Analysis of Electrocautery Versus LigaSure Energy-based Device for Anterolateral Thigh Free Flap Dissection.

Plastic and reconstructive surgery. Global open·2026
Same author

Smartphone-Based Proactive Self-Screening for Ocular Surface Malignancies: A Nonrandomized Clinical Trial.

JAMA ophthalmology·2026
Same author

<i>Trichinella spiralis</i> HSP70 Mediates Mice Immune Responses via TLR2/MyD88/ERK Signaling Pathway.

Transboundary and emerging diseases·2026
Same author

Inhibition of starch retrogradation in fermented rice cakes during simulated cold chain logistics.

Food chemistry·2026
Same author

Chlorogenic acid modulates gut microbiota and metabolites to alleviate intrahepatic cholestasis of pregnancy: Insights from 16S rRNA sequencing and metabolomics.

Biochemistry and biophysics reports·2026

相关实验视频

Updated: Sep 13, 2025

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
08:56

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

Published on: February 10, 2015

52.8K

同时的非酒精性脂肪性肝病可能会降低肝纤维化严重程度在患有原发性胆道胆炎的患者.

Wenhui Ren1, Zilong Wang2, Xinyue Liu3

  • 1Department of Clinical Epidemiology, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing, 100044, China.

BMC gastroenterology
|July 30, 2025
PubMed
概括
此摘要是机器生成的。

在原发性胆道胆炎 (PBC) 患者中,非酒精性脂肪性肝病 (NAFLD) 没有影响对乌尔索西胆酸 (UDCA) 的生物化学反应. 然而,并发性NAFLD可能会改善PBC中的肝纤维化和长期无移植生存率.

关键词:
生物化学反应的反应长期预后 长期预后非酒精性脂肪性肝病是非酒精性脂肪性肝病.主要胆道胆管炎是一种胆道胆管炎.进展性肝脏纤维化

更多相关视频

Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology
12:36

Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology

Published on: March 14, 2020

16.3K
Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution
04:14

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution

Published on: April 16, 2019

12.1K

相关实验视频

Last Updated: Sep 13, 2025

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
08:56

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

Published on: February 10, 2015

52.8K
Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology
12:36

Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology

Published on: March 14, 2020

16.3K
Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution
04:14

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution

Published on: April 16, 2019

12.1K

科学领域:

  • 肝病学 肝病学是一种肝病学.
  • 内部医学 内部医学
  • 胃肠病学 胃肠病学

背景情况:

  • 原发性胆道胆炎 (PBC) 是一种慢性肝病.
  • 非酒精性脂肪性肝病 (NAFLD) 越来越普遍.
  • NAFLD对PBC进展和预后的影响尚未完全理解.

研究的目的:

  • 调查NAFLD对PBC进展和预后的影响.
  • 评估同时出现的NAFLD如何影响PBC患者对UDCA治疗的生化反应.
  • 评估NAFLD对肝纤维化的影响和PBC的长期存活率.

主要方法:

  • 对PBC患者的回顾性研究,确定那些同时患有NAFLD的患者.
  • 主要结局:对UDCA的完整生化反应 (巴黎标准).
  • 二级结局:非侵入性纤维化得分 (APRI,FIB-4) 和无移植生存率 (GLOBE得分).

主要成果:

  • 24.0%的PBC患者 (87/363) 同时患有NAFLD.
  • 在PBC和PBC+NAFLD组之间对UDCA的生化反应没有显著差异.
  • PBC+NAFLD组显示纤维化得分有所改善 (APRI,FIB-4) 和更好的无移植生存率.

结论:

  • 同时的NAFLD不会显著改变PBC中对UDCA的生化反应.
  • 在PBC患者中,NAFLD可能与改善的肝纤维化和更好的长期预后有关.
  • 需要进一步的研究来阐明这些发现背后的机制.