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关于HCV查策略的范围审查:人口查和测试类型
Saro Abdella Abrahim1, Andrew Radley2, Sarah K Inglis3
1Health Laboratory Services, Ethiopian Public Health Institute, Addis Ababa, Ethiopia. helen_saro@yahoo.com.
BMC public health
|July 30, 2025
概括
肝炎C病毒 (HCV) 查策略对于早期检测至关重要,特别是在资源不足的环境中. 将测试整合到社区中心和诊所中,可以有效地接触到有风险的人群,以便及时诊断和护理.
科学领域:
- 肝病学和传染病的研究
- 公共卫生和流行病学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 肝炎C病毒 (HCV) 构成了全球健康的重大挑战,导致肝脏炎症和损伤.
- 尽管有各种测试策略,但在低收入和中等收入国家 (LMICs) 确诊的HCV病例仍然低于5%.
研究的目的:
- 审查和记录不同C型肝炎病毒 (HCV) 查方法的证据.
- 确定有效的策略,以增加HCV测试采用率和诊断.
主要方法:
- 根据PRISMA指南进行了范围审查.
- 在四个数据库 (Scopus,PubMed,CINAHL,Google Scholar) 的文献搜索中,发现了8318个记录.
- 在选和应用纳入标准后,包括了51项研究.
主要成果:
- 确定了三个主要的HCV查策略:通用,有针对性和基于风险的.
- 查的关键人群包括孕妇,婴儿潮一代,无家可归者和在惩戒设施中的那些人.
- 将HCV查整合到现有的HIV/STI诊所和社区中心,如监狱和康复中心,增加了测试采用率.
结论:
- 查孕妇,婴儿潮一代和高风险群体有效地识别出HCV抗体阳性个体.
- 将HCV查纳入社区服务中心和诊所是一个有效的方法来接触有风险的人群.
- 一种具有成本效益的诊断方法包括HCV抗体测试,然后对抗体阳性个体进行HCV抗原测试.
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