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Updated: Sep 13, 2025

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通过PI3K/AKT/mTOR信号轴,Kdf1调节了牙尖端形态发生

Jiayu Wang1, Miao Yu1, Hangbo Liu1

  • 1Department of Prosthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.

Cell proliferation
|July 31, 2025
PubMed
概括

角质细胞分化因子1 (Kdf1) 对骨尖端的发育至关重要. 在小鼠中,Kdf1的丧失会通过过度激活PI3K/AKT/mTOR通路导致异常的牙形态发生,从而影响细胞增殖.

关键词:
Kdf1 在线播放在PI3K/AKT信号通路中.细胞的增殖细胞的增殖.内部质上皮质是内的表皮.牙尖端的形态生成 牙尖端的形态生成

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