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Updated: Sep 13, 2025

Author Spotlight: Exploring Cellular Processes by Modeling Ligands in Cryo-EM Maps
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Mn2+加速了αIIbβ3整合素的联结位点激活:来自全原子模拟的洞察

Robert E Coffman1, Reza Kolasangiani2, Tamara C Bidone3

  • 1Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, Utah.

Biophysical journal
|July 31, 2025
PubMed
概括

(Mn2+) 通过促进结合部位的更快的结构变化来加速整合素激活. 这模仿生理激活,但比/ (Mg2+/Ca2+) 更快地发生.

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