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Updated: Sep 13, 2025

Porous Silicon Microparticles for Delivery of siRNA Therapeutics
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对生物寡合体与siRNA复合的分子洞察力,用于治疗应用

Desh Deepak Yadav1, Debdip Bhandary2, Pradip Paik1

  • 1School of Biomedical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, Uttar Pradesh 221005, India.

The journal of physical chemistry. B
|July 31, 2025
PubMed
概括

作为小干扰RNA (siRNA) 传递的载体,N-烯-氨甲基 (NAPA) 寡合体显示出有前途的潜力. 分子动力学模拟揭示了稳定的复合物,其中五聚为向RNA疗法提供了最大的紧缩和稳定性.

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