Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Antimicrobial Proteins01:23

Antimicrobial Proteins

5.4K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
5.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A Novel Recombinant Protein Purification Approach Using Biomolecular Condensates.

International journal of molecular sciences·2026
Same author

A Novel Strategy for Highly Efficient Heterologous Expression of Carbonic Anhydrase in <i>Yarrowia lipolytica</i>.

International journal of molecular sciences·2026
Same author

High-Intensity Pulse Magnetic Fields Affect Redox Homeostasis and Survival Rate of <i>Escherichia coli</i> According to Initial Level of Intracellular Glucose.

Biomolecules·2025
Same author

De Novo Design of High-Affinity HER2-Targeting Protein Minibinders.

Biomolecules·2025
Same author

CARF-dependent preferential RNA cleavage by Csm6 increases drug susceptibility of mycobacteria.

Nucleic acids research·2025
Same author

A xylenol orange-based pH-sensitive sensor array for identification of bacteria and differentiation of probiotic drinks.

Analytical methods : advancing methods and applications·2024

相关实验视频

Updated: Sep 13, 2025

Biomimetic Materials to Characterize Bacteria-host Interactions
12:22

Biomimetic Materials to Characterize Bacteria-host Interactions

Published on: November 16, 2015

9.5K

以贝类脚为灵感的多功能工程蛋白质粘合剂,具有增强的抗菌性能.

Zitang Xu1, Kai Li1, Siqiang Wang1

  • 1Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, P. R. China.

Biomacromolecules
|July 31, 2025
PubMed
概括

开发了一种新的生物灵感粘合蛋白,M5EP,具有强大的粘合和抗菌特性. 这种蛋白质对工业和生物医学应用都很有前途,为传统粘合剂提供了更安全的替代品.

更多相关视频

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

22.2K
TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application
08:40

TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application

Published on: June 8, 2016

14.3K

相关实验视频

Last Updated: Sep 13, 2025

Biomimetic Materials to Characterize Bacteria-host Interactions
12:22

Biomimetic Materials to Characterize Bacteria-host Interactions

Published on: November 16, 2015

9.5K
Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

22.2K
TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application
08:40

TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application

Published on: June 8, 2016

14.3K

科学领域:

  • 生物材料科学 生物材料科学
  • 蛋白质工程是指蛋白质的工程.
  • 粘合技术的技术 粘合技术

背景情况:

  • 传统的粘合剂对环境和健康构成风险.
  • 基于蛋白质的材料为粘合剂应用提供生物相容性和可设计性.
  • 贝类脚蛋白和弹性质是先进生物材料的自然灵感来源.

研究的目的:

  • 设计和表达一种新的粘合蛋白,M5EP,灵感来自贝脚蛋白5和弹性纤维素.
  • 评估M5EP的粘合性和抗菌活性.
  • 评估M5EP在工业和生物医学领域的生物相容性和潜在应用.

主要方法:

  • M5EP的设计灵感来自贝脚蛋白5和弹性质.
  • 在 *Escherichia coli* BL21(DE3) 中实现了M5EP的有效表达.
  • 铁酶催化剂被用来激活M5EP到其成熟的形式,M5EPm,使粘附.

主要成果:

  • 在各种接口上,M5EPm的粘合强度超过2 MPa (干燥) 和0.2 MPa (潮湿).
  • 无论是M5EP还是M5EPm,都显示出对大肠杆菌和金黄色葡萄球菌有显著的抗菌活性.
  • 在体外研究证实了M5EP的有利的血小板凝固特性和生物相容性.

结论:

  • 新型生物灵感粘合蛋白M5EP具有强大的粘合和抗菌能力.
  • M5EP在工业粘合剂市场和生物医学应用中都有很大的应用潜力.
  • 这种基于蛋白质的粘合剂为传统粘合剂提供了一个生物相容和环保的替代品.