相关实验视频
Updated: Sep 13, 2025

07:14
Acupuncture in a Rat Model of Asthma
Published on: August 25, 2020
6.1K
亚洲基于指南的喘治疗:来自强大的时间状态模型的见解
Laura Huey Mien Lim1, Yah Ru Juang1, Mei Fong Liew2,3,4
1Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
The journal of allergy and clinical immunology. Global
|July 31, 2025
概括
在亚洲,特别是新加坡,优化喘治疗可以显著降低经济和人文负担. 改善吸入性皮质类固醇 (ICS) 与长效β-激动剂 (LABA) 和减少短效β-激动剂 (SABA) 的坚持,降低使用成本并改善生活质量.
科学领域:
- 肺部医学 肺部医学
- 卫生经济学 卫生经济学
- 公共卫生 公共卫生
背景情况:
- 在亚洲,基于指南的喘管理缺乏全面的数据.
- 了解当前喘治疗的经济和人文影响至关重要.
研究的目的:
- 预测亚洲国家基于指南的喘治疗的长期经济影响.
- 将新加坡作为模型喘治疗结果的案例研究.
主要方法:
- 在亚洲人群中 (2014-2024) 对喘患病率,吸入性皮质类固醇 (ICS) /ICS长效β-激动剂 (LABA) 坚持性和短效β-激动剂 (SABA) 使用的系统审查.
- 开发一个时间状态模型来评估坚持和SABA使用对不受控制的喘负担的影响 (2024-2043).
- 在新加坡损失的20年直接成本,间接成本和质量调整寿命年 (QALYs) 的预测.
主要成果:
- 亚洲的喘患病率在1%-14%之间.
- 报告的ICS/ICS-LABA坚持程度差异很大 (10-90%),平均每年SABA使用量为2.5-6.4.
- 在新加坡,失控的喘预计将花费SGD2772亿美元 (直接),SGD5670亿美元 (间接),在目前的趋势下,在20年内损失了58,872个QALY. 优化治疗可以分别减少27.7%,23.8%和28.8%.
结论:
- 在亚洲,基于指南的喘治疗的基于人口的证据是有限的.
- 经济建模表明,通过优化喘管理,可以大幅减少社会负担.
- 调查结果强调了亚洲国家如新加坡在经济和人文方面的巨大利益的潜力.
相关概念视频
Asthma-IV: Diagnostic and Management
2.6K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.6K
Asthma-IV: Nursing Management
3.3K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
First, in...
3.3K
Asthma: Pathogenesis and Management
597
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
597
Asthma-II: Pathophysiology and Classification
2.9K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.9K
Asthma-I: Introduction
2.8K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.8K
COPD: Management Using Bronchodilators and Corticosteroids
314
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
314

