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Updated: Sep 13, 2025

Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells
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依赖FMRP的翻译控制负面调节了适应蛋白复合体2介导的内细胞分裂

Liang Shi1, Adam Kosti1, Nisha Raj1

  • 1Department of Cell Biology, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.

iScience
|July 31, 2025
PubMed
概括

脆弱X综合征涉及脆弱X信使核糖蛋白 (FMRP) 的损失,影响大脑发育. 这项研究揭示了FMRP通常会抑制像AP-2这样的蛋白质的翻译,从而防止神经元中的过度受体内细胞分裂.

关键词:
细胞生物学 细胞生物学神经科学是一个神经科学.

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