甲状腺癌负担的时间趋势和地理差异:1990年至2021年的全球分析
Zuzhi Zhao1, Yinghao Fan1, Peng Sun1
1Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Frontiers in nutrition
|July 31, 2025
概括
全球甲状腺癌发病率在过去40年里有所上升. 这项研究追踪了从1990年到2021年的甲状腺癌患病率,发病率和死亡率,揭示了疾病负担的全球显著差异.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 在瘤学瘤学.
背景情况:
- 在过去的40年里,甲状腺癌的全球发病率呈现出一致的增长.
- 了解甲状腺癌患病率,发病率,死亡率和残疾调整寿命年 (DALYs) 的当前趋势对于公共卫生至关重要.
- 分析按性别,年龄和社会人口指数 (SDI) 分层,以捕捉详细的流行病学模式.
研究的目的:
- 为提供全球甲状腺癌负担的最新评估.
- 从1990年到2021年分析流行,发病率,死亡率和DALY的趋势.
- 调查甲状腺癌发病率的地理和社会人口差异.
主要方法:
- 利用了2021年全球疾病负担,伤害和风险因素研究 (GBD) 的数据.
- 计算估计的年度百分比变化 (EAPC) 来评估时间趋势.
- 评估流行率 (ASPR),发病率 (ASIR),死亡率 (ASDR) 和DALYs的年龄标准化率.
主要成果:
- 在2021年,全球甲状腺癌负担达到1,987,148.5例.
- 从1990年到2021年,年龄标准化流行率 (ASPR) 和发病率 (ASIR) 在全球范围内增加.
- 虽然年龄标准化死亡率 (ASDR) 和DALY率出现下降,但仍存在显著的地理差异,高收入地区显示出更高的ASPR/ASIR,较低的SDI地区显示出更高的ASDR.
结论:
- 甲状腺癌的全球健康负担在1990年至2021年间显著增加.
- 甲状腺癌发病率的明显地理差异凸显了有针对性的公共卫生干预措施的必要性.
- 预防和控制策略必须解决甲状腺癌全球分布不平等的问题.
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