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Updated: May 8, 2026

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预测直肠癌中新辅助化疗或放射治疗反应:从生物标志物到临床实践的见解

Hikmet Pehlevan-Özel1, Eda Şahingöz2, Mert Altaş3

  • 1Department of Surgery, Ankara City Hospital, Ankara 06800, Türkiye.

World journal of gastrointestinal surgery
|July 31, 2025
PubMed
概括

预测直肠癌中新辅助化疗或放射治疗反应至关重要. 本综述研究了生物标志物,以改善局部晚期直肠癌的治疗选择和患者的治疗结果.

关键词:
生物标志物 生物标志物临床预测因素 临床预测因素新辅助性化疗或放射治疗.病理完整反应的病理完整反应.无线电学 (Radiomics) 是一种无线电学.这是直肠癌.瘤回归分级的分级方法

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...