关于女性化生殖器性别确认手术研究的核心结果:来自GenderCOS项目的研究结果
Marleen S Vallinga1,2, Philippine J Roijer1,2, Thomas E Pidgeon3
1Department of Plastic, Reconstructive and Hand Surgery, Amsterdam UMC (Location VUmc) - Amsterdam University Medical Centre, Amsterdam, the Netherlands.
EClinicalMedicine
|July 31, 2025
概括
一个新的核心成果集 (COS) 标准化了女性化生殖器性别确认手术 (gGAS) 的结果. 这旨在通过确保一致的结果测量来提高研究质量和患者护理.
科学领域:
- 肯定性别的护理.
- 手术成果研究的研究结果.
- 患者为中心的结果.
背景情况:
- 女性化生殖器性别确认手术 (gGAS) 涉及各种程序,报告结果各异.
- 当前研究中的异质性阻碍了知情决策和比较分析.
- 结果测量的标准化对于推进该领域至关重要.
研究的目的:
- 开发一个基于共识的核心成果集 (COS),用于使生殖器性别确认手术变得女性化.
- 建立一个标准化的框架,用于测量和报告gGAS研究的结果.
主要方法:
- 一个多学科的国际指导小组指导了COS的发展.
- 通过文献审查和对跨性别人士的焦点小组确定了结果.
- 为了达成协议,举行了国际德尔菲研究和共识会议.
主要成果:
- 最初的2621个结果被改进为39个德尔菲过程.
- 最终的共识为女性化gGAS产生了11个核心结果.
- 在11个结局中,有6个是患者报告的;有7个适用于广泛,有4个是针对阴道整形手术的.
结论:
- 开发的COS将在女性化gGAS研究中标准化结果测量.
- 采用这种COS可以减少结果的异质性,提高研究质量.
- 标准化报告最终将改善接受gGAS的跨性别人士的护理质量.
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