结核软组织感染患者的临床概况和结果:一项前性观察性研究
Piyush Sharma1, N Karthik1, Mayank Badkur1
1General Surgery, All India Institute of Medical Sciences, Jodhpur, Jodhpur, IND.
Cureus
|July 31, 2025
概括
死亡软组织感染 (NSTI) 的管理是复杂的. 高风险分数和低专素预测死亡率,而及时的多学科护理改善了NSTI患者的结果.
科学领域:
- 传染性疾病 传染性疾病
- 手术感染 手术感染
- 关键护理医学 关键护理医学
背景情况:
- 死亡软组织感染 (NSTI) 提出了复杂的管理挑战.
- 不同的临床症状,并发症和微生物原因使NSTI治疗复杂化.
- 了解NSTI的临床特征和死亡率因素至关重要.
研究的目的:
- 分析NSTI患者的临床特征.
- 在NSTI中识别微生物模式.
- 确定影响NSTI病例死亡率的因素.
主要方法:
- 在一个单一中心进行前性观察研究.
- 包括87名被诊断患有NSTI的成年患者.
- 主要结局:手术时间对死亡率的影响;次要:病因,植物,并发病,结局.
主要成果:
- 87名患者 (74.7%的男性,18-88岁) 被纳入;18人死亡 (20.7%).
- 干预的平均时间为6小时,幸存者和非幸存者之间没有显著差异.
- 大肠杆菌是最常见的分离物;观察到对和基诺的抗性增加.
结论:
- 较高的APACHE II和LRINEC分数,贫血,低albuminemia和高肌素是死亡率预测因素.
- 迅速,多学科的管理是改善NSTI患者结果的关键.
- 早期手术干预的时间对这一队列的死亡率没有显著影响.
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