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Updated: Sep 13, 2025

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单-ADP-ribosylating PARP酶在细胞信号和疾病中的作用

Simone Di Paola1, Giovanna Grimaldi1, Daniela Corda1

  • 1Institute of Endotypes in Oncology, Metabolism, and Immunology 'G. Salvatore' (IEOMI), National Research Council (CNR), Via Pietro Castellino 111, 80131, Naples, Italy.

Journal of cell science
|July 31, 2025
PubMed
概括

通过单一ADP-ribosyl转移酶 (ARTs) 进行单一ADP-ribosylation (MARylation) 调节细胞循环和应激反应等关键细胞过程. 了解MARylation目标对于开发用于病毒感染和癌症的新疗法至关重要.

关键词:
癌症 癌症 癌症 癌症细胞信号传输 细胞信号传输疾病 疾病 疾病一个ADP-ribosylation-ribosylation,一个ADP-ribosylation,一个ADP-ribosylation-ribosylation.在PARPs中,PARPs是非常重要的.

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