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预测中国和欧洲近视发病率的因素
Nina Tahhan1,2, Xiangui He3, Kathryn Saunders4
1Brien Holden Vision Institute (BHVI), Sydney, New South Wales, Australia.
概括
与欧洲儿童相比,中国儿童的近视发病风险更高. 球形等效 (SE) 是最强的预测因素,中国人的眼睛需要更大的超视储备来防止近视.
科学领域:
- 眼科医生 眼科 眼科
- 人口健康 人口健康
- 遗传学 是一个遗传学.
背景情况:
- 近视发病率是一个日益增长的全球健康问题.
- 预测模型对于早期干预和预防策略至关重要.
- 了解近视发展的种族和区域差异至关重要.
研究的目的:
- 开发和验证中国和欧洲儿童近视发病率的预测模型.
- 为了确定与近视发作相关的关键风险因素.
- 为了比较种族之间的近视发病率和预测因子有效性.
主要方法:
- 对来自英国,瑞典和中国的4405名非近视儿童的数据进行了纵向分析.
- 使用了卡普兰-梅尔和考克斯的比例危险模型.
- 评估的预测因素包括年龄,性别,父母近视,循环的球形等价值 (SE),轴长 (AL) 和轴长/角膜曲率半径 (AL/CR).
主要成果:
- 24个月的近视发病率为中国儿童的18.8%,欧洲儿童的6.7%.
- 确定了关键的风险因素:中国人,年龄较小,女性,父母近视,较少高视力SE,高AL/CR.
- 球体等效 (SE) 显示出最高的预测准确度 (C-统计值为0.90).
结论:
- 球体等效 (SE) 是两种种族近视发病率的最重要的预测指标.
- 虽然预测因素通常相似,但中国儿童面临更高的风险,需要更大的超视储备.
- 这些发现支持对近视发病率的特定种族预测工具的开发.
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