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Updated: Sep 13, 2025

Ultrasonic Assessment of Myocardial Microstructure
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在临床前评估阿托瓦斯塔丁用于治疗内心纤维缩症

Daniel Diaz-Gil1, Gregor Gierlinger2, Natalia Silva-Gomez3

  • 1Department of Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts, USA; Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts, USA; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA; Department of Pediatrics, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA; Department of Pediatric Heart Medicine and Adults with Congenital Heart Disease, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

JACC. Basic to translational science
|July 31, 2025
PubMed
概括

阿托瓦斯塔丁降低了内心内皮细胞中的纤维素激活,这是内心纤维elastosis的一个关键过程. 这项研究表明,阿托瓦斯塔丁增加了保护性KLF2表达,为相关心脏病提供了潜在的治疗策略.

关键词:
亚托尔瓦斯塔丁是一种遗传性心脏病是一种先天性心脏病.内心纤维延展症 内心纤维延展症细胞内皮 - 介质细胞过渡低可塑性左心综合征是什么

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