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Updated: Sep 13, 2025

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PI3K/Akt信号通路调节了参与抗癌免疫治疗耐药性的CD155表达

Katsushige Kawase1, Shusuke Kawashima2, Tatsuya Nishi3

  • 1Chiba Cancer Center, Chiba-shi, Chiba, Japan.

Cancer immunology research
|July 31, 2025
PubMed
概括

对PD-1阻断疗法的耐药性是一个挑战. 这项研究确定了双特异性氨酸-酸酸化调节激酶1A (DYRK1A) 和PI3K/Akt信号作为CD155表达的关键调节者,提供了克服癌症治疗耐药性的潜在策略.

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