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ASXL1 缺乏导致表观遗传功能障碍,联合免疫缺陷和EBV相关淋巴瘤

Maggie P Fu1,2, Mehul Sharma3, Pariya Yousefi3

  • 1British Columbia Children's Hospital, Centre for Molecular Medicine and Therapeutics, Department of Medical Genetics, University of British Columbia , Vancouver, Canada.

The Journal of experimental medicine
|July 31, 2025
PubMed
概括

一种新的天生的免疫错误 (IEI) 是由ASXL1基因变异引起的. 这种情况会影响免疫细胞的功能,导致慢性病毒感染和恶性瘤.

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