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Updated: Sep 13, 2025

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
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该DNA复制检查点针对kinetochore重新定位DNA结构诱导的复制损伤到核外围

Tyler M Maclay1, Jenna M Whalen1, Matthew J Johnson1

  • 1Department of Biology, Tufts University, Medford, MA 02155, USA.

Cell reports
|July 31, 2025
PubMed
概括

通过将它们移动到核孔综合体,可以克服由毛针形成的CAG/CTG重复所带来的DNA复制挑战. 这种重新定位依赖于复制检查点和DNA损伤诱导的微管.

关键词:
科普:分子生物学 分子生物学检查点是DNA复制检查点.亨廷顿病就是亨廷顿病.中心释放的中心释放造成损伤的诱导性微管头发结构 头发结构核孔是一个核孔.三核酸重复的重复没有配合的叉子.

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