相关实验视频

Updated: Sep 13, 2025

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Published on: March 4, 2014

手部功能障碍在女性RA和psA患者中更为明显,并且在没有同时出现手部炎症的患者中也发现

Birte Coppers, Simon Heinrich¹, Sara Bayat

¹Institute of Applied Dynamics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, GERMANY.

Medicine and science in sports and exercise

|July 31, 2025

概括

在类风湿性关节炎 (RA) 和牛皮性关节炎 (PsA) 患者中,手部功能显著受损,特别是在女性中. 这种损伤即使没有活跃的手部炎症也会持续存在,影响握力和精细运动技能.

科学领域:

类风湿病学类风湿病学
整形外科整形外科整形外科
物理疗法物理治疗

背景情况:

手的功能对于患有类风湿性关节炎 (RA) 和牛皮性关节炎 (PsA) 的患者的日常活动至关重要.
在炎症性关节炎管理中,全面的手部功能评估未得到充分利用.
了解手部功能缺陷是改善RA和PsA患者生活质量的关键.

研究的目的:

为了全面评估和比较RA和PsA患者的手部功能,与健康对照对比.
调查疾病活动得分与手部功能障碍之间的关联.
探索性别特异性差异以及并发性炎症对手部功能的影响.

主要方法:

涉及RA,PsA患者和健康对照 (HC) 的横截面研究.
使用同度握力,动态握力和精细运动技能 (莫伯格拾起测试) 评估手部功能.
统计分析采用了线性混合效应模型,按性别分层,并分析了没有并发手炎的子组.

主要成果:

与HC相比,RA和PsA患者表现出较低的握力和精细运动技能.
损伤在女性患者中更为明显;男性表现出更好的握力维护.
较高的疾病活动分数 (RA的DAS28,PsA的DAPSA) 与动态握力和精细运动技能的降低相关,特别是在女性中.

结论:

在RA和PsA患者中,手部功能同样受到损害.
女性患者体验到更显著的手部功能缺陷.
即使没有活跃的关节炎症,手部功能受损也很明显.

关键词:

生物标志物生物标志物减少疾病活动.精细的运动技能精细的运动技能抓住力量抓住力量松性关节炎松性关节炎风湿性关节炎风湿性关节炎

更多相关视频

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury

Published on: March 21, 2025

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

相关概念视频

Rheumatic Heart Disease I: Introduction

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...