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在猪胸腔镜中使用双肺通风的外科工作空间
Willem van Weteringen1,2, Jan-Wiebe H Korstanje2, Lonneke M Staals3
1Department of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands.
PloS one
|July 31, 2025
概括
在儿科胸腔镜检查中,维持双肺通风需要仔细管理胸头顶部的压力. 高吸气压 (≥6 mmHg) 显著影响心肺功能,腹膜位移创造了大部分的外科工作空间.
科学领域:
- 麻醉学 麻醉学
- 胸部外科手术 胸部外科手术
- 儿科重症监护中心儿童重症监护中心
背景情况:
- 由于专门设备的尺寸限制,双肺通风在儿科胸腔镜检查中很常见.
- 创建手术空间的capnothorax需要控制的灌气压力,以平衡通风和血液动力学.
- 在头胸下管理通风需要经验丰富的麻醉师.
研究的目的:
- 在猪模型中研究头胸气压和心肺呼吸系统效应之间的关系.
- 在双肺通风过程中量化隔膜位移对胸部工作空间的贡献.
- 为了确定儿科胸腔镜的安全吸气压限值.
主要方法:
- 麻醉后的猪 (n=10) 处于左侧卧床位置,接受了体积保证的间歇性正压通风.
- 在增加的二氧化碳灌气压力 (0-10 mmHg) 时获得了终端呼吸CT扫描.
- 测量了头胸部,右肺和左肺的体积;监测心肺呼吸参数.
主要成果:
- 气压≥6mmHg引起了显著的心肺呼吸系统影响,需要内的支持.
- 在10mmHg时,峰值通风压力为35cmH2O,头胸口体积为1503ml.
- 隔膜位移 (79.5%) 是头胸部体积的主要贡献者,其次是肺体积 (16.1%) 和胸部膨胀 (4.4%).
结论:
- 在双肺通风中,胸腔镜工作空间在很大程度上是通过隔膜位移实现的.
- 高度的胸气压对猪的心肺呼吸系统有深远的影响.
- 在使用双肺通风的儿科胸腔镜时,最大限度地降低吸气压力至关重要.
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