评估移动应用程序对慢性疾病药物服药的有效性:系统性审查和元分析
Vaidehee Lanke1, Kevin Trimm2, Bettina Habib1
1Department of Epidemiology, Biostatistics and Occupational Health, McGill University, 2001 McGill College Ave, Montreal, QC, H3A 1Y7, Canada, 1 3062227521.
Journal of medical Internet research
|July 31, 2025
概括
移动应用程序可以显著改善慢性病管理的药物坚持. 这次系统审查发现,应用程序干预措施始终提高了患者的坚持,为长期健康管理提供了有价值的工具.
科学领域:
- 数字健康数字健康
- 药物经济学 药物经济学
- 临床信息学 临床信息学
背景情况:
- 药物坚持对于有效管理慢性疾病至关重要.
- 移动应用程序提供各种功能来支持和增强药物坚持.
- 本次审查侧重于移动应用程序在改善慢性疾病的坚持方面的作用.
研究的目的:
- 系统地评估移动应用程序在促进慢性病患者遵守药物的有效性.
- 综合来自随机对照试验 (RCT) 关于移动应用程序干预药物坚持的证据.
主要方法:
- 对相关RCT进行了对MEDLINE,Embase和Cochrane控制试验中央注册表的系统搜索.
- 质量描述的研究设计和移动应用程序功能.
- 使用随机效应模型和差异分析进行了对药物坚持得分的元分析,如适用.
- 使用柯克兰偏差风险工具评估偏差风险.
主要成果:
- 包括14个RCT (2014-2022) 与各种慢性疾病,最常见的高血压.
- 所有研究都报告了药物坚持的改善,10项研究显示了统计学上显著的改善.
- 分析表明,坚持度得分有显著改善,特别是莫里斯基药物坚持度表-8 (MMAS-8) 和百分比坚持度表.
结论:
- 移动应用程序是改善慢性病患者药物遵守的有效工具.
- 基于应用程序的干预措施显示出成功治疗慢性疾病的潜力.
- 进一步的研究可以探索特定的应用程序功能,以最大限度地提高遵守效益.
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