预后营养指数预测,患有传染病病因的视频辅助胸部手术的患者手术后情况不佳
Jesús J Rosales-de la Rosa1, José B López-Martínez1, Andrea Escamilla-López1
1Departamento de Cirugía, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Gaceta medica de Mexico
|July 31, 2025
概括
预后营养指数 (PNI) 有效地预测胸部手术患者感染的不良结果. 28.69的PNI切线确定了高风险患者,死亡率和并发症增加.
科学领域:
- 胸部外科手术 胸部外科手术
- 外科手术的结果
- 传染性疾病 传染性疾病
背景情况:
- 预后营养指数 (PNI) 尚未被评估为患有感染胸部手术的患者的术后预后结果的预后工具.
- 评估手术预测结果的手术前预测因素对于患者管理至关重要.
研究的目的:
- 为了确定PNI是否可以预测胸部感染手术的患者的不良术后结果.
- 确定PNI作为预后指标在这个特定的手术群体中的实用性.
主要方法:
- 在2019年1月至2023年12月期间,针对胸部感染进行视频辅助胸腔镜手术 (VATS) 的61名患者的回顾性分析.
- 接收器操作特征 (ROC) 曲线分析以确定最佳的PNI截止值 (28.69).
- 高风险 (PNI ≤ 28.69) 和低风险 (PNI > 28.69) 组的比较,使用千平方,费舍尔精确,曼-惠特尼和考克斯回归分析.
主要成果:
- 一个最佳的PNI切线为28.69,在预测结果方面表现出高准确度 (AUC0.860).
- 与低风险患者相比,高风险患者 (19) 的30天死亡率 (42%对2%) 和重大并发症 (68%对16%) 显著增加 (42%对2%),较低风险患者 (42).
- 基于PNI的风险分层是30天死亡率和重大并发症的独立预测因素.
结论:
- 预后营养指数 (PNI) 是针对胸部感染接受VATS治疗的患者手术后不良结果的经过验证和独立预测指标.
- 在这种患者群体中,PNI提供了一种简单但有效的风险分层和术前评估工具.
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