一个全国性的基于人口的新生儿结局在怀孕相关的贝尔的注册研究
Lovisa Lansing1, Elin Marsk1, Sophia Brismar Wendel2
1Department of Otorhinolaryngology, Karolinska University Hospital, Hälsovägen 13, 141 86 Stockholm, Sweden; Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
概括
怀孕期间的贝尔并没有影响新生儿的结果. 然而,在产后期 (puerperium) 的贝尔与新生儿不良结果有关,这表明分娩并发症可能引发这种情况.
科学领域:
- 神经学 神经学
- 产科 产科 产科 产科 产科
- 新生儿科学 新生儿科学
背景情况:
- 贝尔 (面部神经) 在怀孕期间和产后期间更频繁地观察到.
- 这种发病率增加的原因尚不清楚.
- 这项研究调查了贝尔在这些关键的孕产妇时期对新生儿健康结果的影响.
研究的目的:
- 评估怀孕期间贝尔和产后期 (产后头两个月) 和新生儿不良结果之间的关联.
- 为了确定与婴儿期贝尔相关的危险因素.
主要方法:
- 从2005年到2015年,瑞典进行了一项全国性的队列研究.
- 来自国家患者登记册和医疗出生登记册的数据被合并,以识别怀孕或产后期间患有贝尔的妇女.
- 使用多变量逻辑回归分析来确定风险因素及其关联,计算调整的几率比率 (aOR) 和95%置信区间 (CI).
主要成果:
- 总共有2,051名怀孕相关贝尔的妇女被确定 (怀孕期间1,191名,产后860名).
- 怀孕期间的贝尔麻与新生儿不良结果没有关联.
- 在产后的贝尔与新生儿不良结果有关 (aOR 1.27,95% CI 1.06-1.52).
- 产后贝尔的危险因素包括非非洲/南美血统,多重怀孕,孕前,分娩感染和外周/脊柱麻醉.
结论:
- 新生儿不良后果在婴儿后期的贝尔后更常见,但在怀孕期间并不常见.
- 这些发现表明,分娩期间的不良事件可能会在分娩后期导致贝尔.
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