在局部上肢功能期间的心率动态作为心脏自主功能障碍的新型测量:研究与衰老和疾病相关的变化
Kübra Akbaş1, Mohammad Hosseinalizadeh2,3, Kelsi Petrillo2,3
1Department of Rehabilitation and Movement Sciences, School of Health Professions, Rutgers University, Newark, New Jersey, USA, ka657@shp.rutgers.edu.
Gerontology
|July 31, 2025
概括
老龄化显著影响心脏自主功能,而不是大动脉狭窄. 一个简单的上肢测试可以评估心率 (HR) 动态和心率变化 (HRV),为心脏自主功能障碍提供了一个新的临床工具.
科学领域:
- 心脏病学 心脏病学
- 自主神经系统功能 自主神经系统功能
- 老年学是指老年学的学科.
背景情况:
- 心脏自主功能障碍在衰老和心血管疾病中很常见,例如大动脉狭窄 (AS).
- 运动期间的心率变化 (HRV) 和心率变化 (HR) 评估心脏自主功能.
- 在运动期间测量HR是具有挑战性的,因为运动工件.
研究的目的:
- 使用上肢功能 (UEF) 测试开发一种方法来评估HR指标,使用最小的运动工件来评估HR指标.
- 确定衰老和AS对静止状态HR和HRV的影响.
- 量化人力资源价值和人力资源动态之间的关系.
主要方法:
- 70名参与者 (年轻对照组,老年对照组,患有AS的老年人) 接受了基线休息和UEF测试 (20秒快速肘部曲-延伸).
- 通过心电图测量HR;HRV结果包括SampEn,RMSSD,pNN25和Poincaré图片.
- 测量的HR动态是UEF期间HR的%增加和恢复期间HR的%减少.
主要成果:
- 与年轻对照组相比,老龄化/老年人 (对照组和AS) 的休息状态HR测量 (SampEn除外) 和HR动态显著较低.
- 在老年对照组和AS组之间没有发现HRV的显著差异.
- 在较旧的对照组和AS组之间,HRV下降有显著差异,HRV参数与HR动态有显著的相关性.
结论:
- 老龄化对HRV和HR动态的影响比AS更为明显.
- 通过简短的体检来评估HR动态,可以作为心脏自主功能障碍的潜在临床措施.
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