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Updated: Sep 13, 2025

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在质母细胞瘤中,GPRC5A通过糖溶性重编程来调节对temozolomide的耐药性

Wahafu Alafate1, Shichao Du2, Shiyue Pan1

  • 1Department of Neurosurgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.

International journal of biological macromolecules
|July 31, 2025
PubMed
概括

多型质母细胞瘤 (GBM) 涉及上调的GPRC5A,促进化学抵抗和低生存率. 针对GPRC5A和GLUT1相互作用可能会改善质母细胞瘤治疗结果.

关键词:
化学抗药性 化学抗药性是一种抗药性.在 GPRC5A 中.泰莫佐洛米德 (Temozolomide) 是一种可怕的药物.

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