与非自杀性自我伤害的年轻成年人的情绪反应和调节相关的神经活动差异
Gyumyoung Kim1, Hyemin Shin2, Ji-Won Hur1
1School of Psychology, Korea University, Seoul, Republic of Korea.
BJPsych open
|July 31, 2025
概括
非自杀自伤 (NSSI) 个体表现出不同的大脑活动模式,在情绪反应过程中反应加剧,在情绪调节过程中反应减少. 这些发现表明,对于情绪处理缺陷,有新的治疗点.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 心理学 心理学 心理学
背景情况:
- 情绪处理困难是非自杀性自伤 (NSSI) 的核心.
- 在NSSI中这些情绪缺陷背后的神经机制仍然不太清楚.
研究的目的:
- 在NSSI患者中调查情绪反应和调节中的神经变化.
- 检查情绪价值 (正/负) 和观察到的神经模式之间的关系.
主要方法:
- 功能性磁共振成像 (fMRI) 用于扫描未经药物治疗的年轻成年人进行NSSI (n=29) 和匹配的对照 (n=25).
- 参与者完成了一项情绪调节任务,涉及观看和响应情感唤起的图像.
主要成果:
- 在消极情绪反应过程中,NSSI组显示右上状 (STG),近海马状和上边状的激活增加.
- 在消极情绪调节期间,NSSI组表现出补充运动区域,下额头,门,丘脑和STG中的激活减少.
- 在NSSI患者中观察到情绪反应期间的过度激活和情绪调节期间的低活性,这与情绪失调有关.
结论:
- 患有NSSI的个体在情绪处理中表现出独特的神经模式,其特点是反应性期间的过度激活和调节期间的低活性.
- 这些发现为开发改善NSSI情绪处理的干预措施提供了神经生理学基础.
- 针对这些特定的神经通路可能会增强适应性情绪处理,减少自我伤害行为.
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