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Updated: Sep 13, 2025

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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Published on: September 18, 2014

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苏莫从独特的长串重复中运行,以保持天生的免疫力

Amandine Goffeney1,2,3, Ivo A Hendriks4, Victoria Morel1,2,3

  • 1Nuclear Organization and Oncogenesis Unit, Department of Cell Biology and Infection, Institut Pasteur, Université Paris Cité, 75015 Paris, France.

Nucleic acids research
|July 31, 2025
PubMed
概括

基化通过控制髓状细胞中的IFNB1基因来抑制先天免疫力. 抑制sumoylation会破坏这种抑制,通过I型干扰素反应激活抗瘤免疫力.

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