手术前甲状腺状况对接受甲状腺切除术的格雷夫斯病患者临床结果的影响
Po-Sheng Lee1, Jui-Yu Chen2,3,4, Po-Chung Kuo2,3
1Department of Medicine, Division of Endocrinology and Metabolism, Taipei Veterans General Hospital, Taipei, Taiwan.
World journal of surgery
|July 31, 2025
概括
甲状腺切除术对于患有手术前甲状腺毒素症的格雷夫斯病患者来说是安全的,只要做好最佳准备. 这支持手术,即使在手术前没有达到完全的甲状腺功能状态.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 甲状腺学 甲状腺学
背景情况:
- 手术指南建议在甲状腺切除手术前进行顺利甲状腺治疗,以尽量减少并发症.
- 由于药物不耐受性,耐火性疾病或手术紧急情况,在甲状腺切除前实现安甲状腺症并不总是可行的.
研究的目的:
- 评估手术前甲状腺状况,特别是甲状腺毒性病对格雷夫斯病患者手术结果的影响.
主要方法:
- 81名接受甲状腺切除术的格雷夫斯病患者 (2019-2023) 的回顾性研究.
- 在手术前甲状腺毒性病患者和euthyroid患者之间比较手术结果.
- 收集了有关人口统计,甲状腺功能,并发症,术后管理,并发症和住院的数据.
主要成果:
- 33.3%的患者患有手术前的甲状腺毒性,显示较高的Burch-Wartofsky分数和改变的生化标志物.
- 术后果 (低热血症,血瘤,声,失血,手术时间) 在甲状腺毒性和euthyroid组之间是可比的.
- 没有发生甲状腺风暴或死亡;住院时间没有显著差异.
结论:
- 甲状腺切除术是安全的在选择的格雷夫斯病患者与手术前的甲状腺毒素,当提供最佳的准备.
- 支持甲状腺切除术的可行性,当不能在手术前实现完全的生物化学甲状腺功能减退时.
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