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在高尔德综合征和阿尔波特综合征中,IV原蛋白

Dawiyat Massoudi1, Jeffrey H Miner2, Douglas B Gould3,4

  • 1Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.

Nature reviews. Nephrology
|July 31, 2025
PubMed
概括

原IV (COL4A1-COL4A6) 的遗传变异会导致古尔德综合征 (GS) 和阿尔波特综合征 (AS),影响多个器官. 基因编辑为这些疾病提供了潜在的治疗策略.

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