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Updated: Sep 13, 2025

Extremely Rapid and Specific Metabolic Labelling of RNA In Vivo with 4-Thiouracil Ers4tU
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Published on: August 22, 2019

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在拼接之前,queuosine被纳入前体tRNA中.

Wei Guo1,2,3, Igor Kaczmarczyk4,5, Kevin Kopietz6

  • 1Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.

Nature communications
|July 31, 2025
PubMed
概括

新转录的tRNA分子需要修改功能. 这项研究表明,queuosine (Q) 修饰发生在eukaryotes的tRNA拼接之前,澄清了tRNA成熟的关键步骤.

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