在绝经后的乳腺癌幸存者中,MIND饮食及其成分与认知功能的关联
Timothy R Winschel1, Kellie Weinhold1, Patrick M Schnell2
1Human Nutrition Program, Department of Human Sciences, The Ohio State University, Columbus, OH, 43210, USA.
概括
富含蔬菜和鱼类的MIND饮食模式与乳腺癌幸存者化疗后认知功能的改善有关. 坚持这种饮食支持更好的记忆力和注意力.
科学领域:
- 神经科学是一个神经科学.
- 营养科学 营养科学
- 在瘤学瘤学.
背景情况:
- 与癌症相关的认知障碍,通常被称为"化疗大脑",影响了许多乳腺癌幸存者.
- 化疗可以导致记忆力,注意力和执行功能的持续缺陷.
研究的目的:
- 研究地中海-DASH干预神经退行性延迟 (MIND) 饮食与乳腺癌幸存者的认知功能之间的关联.
- 检查MIND饮食的特定成分与化疗后的认知表现之间的关系.
主要方法:
- 一项涉及21名绝经后乳腺癌幸存者在完成化疗后一年内进行的横截面研究.
- 用客观测试评估认知功能,通过食物频率问卷和营养生物标志物评估饮食摄入量.
- 使用线性回归模型分析了MIND饮食坚持和认知结果之间的关联.
主要成果:
- 对MIND饮食的更高坚持与全球认知得分,情节性记忆,注意力/工作记忆和语音流性有关.
- 特定的MIND饮食成分,包括非鱼,蔬菜和豆类,显示出与认知表现的积极关联.
- 血液生物标志物,如多可沙赫萨酸 (DHA),与更好的认知功能相关,支持饮食发现.
结论:
- 坚持MIND饮食模式与乳腺癌幸存者化疗后认知功能的增强有关.
- MIND饮食的关键饮食成分可能在保护这一群体的认知能力方面发挥保护作用.
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