治疗性超声波对内皮功能的影响:系统性审查和元分析
Léo José Rubin Neto1, Antonio Marcos Vargas da Silva1, Katieli Santos de Lima1
1Department of Physiotherapy and Rehabilitation, Rehabilitation Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Physiotherapy theory and practice
|August 1, 2025
概括
低强度治疗性超声波 (LITUS) 显著改善了人类内皮功能. 脉冲和连续波形的LITUS都显示出对血管平衡的好处,这表明了治疗潜力.
科学领域:
- 心血管医学 心血管医学
- 生物医学工程 生物医学工程
- 生理学 生理学 生理学
背景情况:
- 血管内皮在调节毛细血管的透性和炎症方面发挥着至关重要的作用.
- 内皮功能是心血管风险和死亡率的关键预测因素.
- 低强度治疗性超声波 (LITUS) 对内皮功能的影响尚不清楚.
研究的目的:
- 系统地审查和分析评估LITUS对人类内皮功能影响的临床试验.
- 评估LITUS在改善血管平衡中的有效性.
主要方法:
- 对安慰剂受控随机临床试验的系统审查和元分析.
- 在多个数据库 (PubMed,Cochrane CENTRAL等) 进行了搜索. 在2025年2月之前.
- 评估偏差风险使用柯克兰偏差风险2.0和GRADE证据的确定性.
主要成果:
- 包括5项试验,包括103名受试者.
- 利图斯通过脉冲波形 (SMD:0.88) 和连续波形 (SMD:1.09) 改善了内皮功能.
- 对脉冲波形和连续波形的证据确定性被评为"中等".
结论:
- 脉冲和连续波形的LITUS有效地增强内皮功能.
- 治疗性超声波应用证明了对血管平衡的好处.
- 作为改善内皮质健康的治疗干预措施,LITUS显示出希望.
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