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氨酸C通过抑制PI3K/AKT/NF-κB信号通路来减轻骨关节炎的发展

Jiawei Hu1, Kai Xiao1, Jianhui Liang2

  • 1Department of Orthopedics, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.

Journal of cellular and molecular medicine
|August 1, 2025
PubMed
概括

来自Pulsatilla chinensis的Pulchinenoside C (PC) 在骨关节炎 (OA) 治疗中显示出有前途. 这种化合物通过调节关键信号通路来有效减少炎症并保护软骨,这表明它在控制OA进展方面可能发挥治疗作用.

关键词:
在PI3K/AKT/NF-κBB中.软骨的退化 软骨的退化骨关节炎是一种关节炎.聚化C 聚化C热致灭 (pyroptosis) 是一种致的过程.

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