神经疾病研究中的门德尔随机化趋势:一个参考文献分析
Shengnan Yin1, Kudelati Zakeer2, Zekun Ma1
1Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Frontiers in neurology
|August 1, 2025
概括
图书统计分析显示,门德尔的随机化 (MR) 是神经疾病研究的一个越来越重要的工具. 国际合作是推动这一领域发展的关键,以更好地预防和治疗.
科学领域:
- 神经学 神经学
- 遗传学 是一个遗传学.
- 流行病学 流行病学
背景情况:
- 门德尔随机化 (MR) 越来越多地被用于复杂疾病研究.
- 了解MR在神经疾病中的应用和趋势至关重要.
研究的目的:
- 在神经疾病研究中对孟德尔随机化进行文献计量分析.
- 确定研究热点,协作模式和地理分布.
主要方法:
- 从科学网络数据库 (2014-2024) 中对出版物的图书统计分析.
- 量化研究出版物量,研究主题,和国际合作.
- 关键词同时出现的分析,以确定突出的研究领域.
主要成果:
- 神经系统疾病的MR研究显著增长,其中关键领域包括中风和心血管疾病.
- 在这一领域,全基因组关联研究经常与MR有关.
- 中国,英国和美国领导国际合作努力.
结论:
- 门德尔随机化显示了研究神经系统疾病的巨大潜力.
- 国际合作对于推进神经病学MR研究至关重要.
- 未来的研究应该专注于跨学科的工作和疾病机制的探索.
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