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Updated: Sep 13, 2025

Development of Compendium for Esophageal Squamous Cell Carcinoma
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通过METTL14介导的m6A甲基化稳定OTUD7B驱动HIF-1α表达在食道状细胞癌中的表达

Fei Ren1, Yansen Cai2, Yang Song1

  • 1Laboratory Animal Centre, Changzhi Medical College, Changzhi, 046000, China.

Oncology research
|August 1, 2025
PubMed
概括

卵巢瘤二基因酶7B (OTUD7B) 通过通过N6-甲基氨酸 (m6A) 甲基化稳定缺氧诱导因子-1α (HIF-1α),在食道状细胞癌 (ESCC) 中起到瘤基因作用. 针对METTL14-OTUD7B途径为ESCC提供了一个潜在的治疗策略.

关键词:
食管状细胞癌 (ESCC) 是一种N6 - 甲基氨酸 (m6A) 的使用.缺氧诱导因子-1α (HIF-1α)类似甲基转移酶14 (METTL14) 的卵巢瘤二维基因酶7B (OTUD7B) 的使用无处不在的化

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