相关实验视频

Updated: Sep 13, 2025

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment

Published on: November 17, 2018

城市猫的肠道微生物组的组成,抗生素耐药性和功能

Ricardo David Avellán-Llaguno^1,2, An Xie^1,3,4, Alex Ujong Obeten^1,4

¹State Key Laboratory of Regional and Urban Ecology, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, PR China.

Environmental science & technology

|August 1, 2025

概括

城市猫是城市的猫.

科学领域:

兽医微生物学兽医微生物学
城市生态学城市生态学
公共卫生公共卫生

背景情况:

肠道微生物群在宿主健康和疾病中起着至关重要的作用.
城市环境给物带来了独特的挑战和风险.
了解城市猫的肠道微生物群对于评估健康风险至关重要.

研究的目的:

为了研究不同城市猫种群的肠道微生物群的组成和功能.
为了确定微生物多样性,抗生素耐药性基因和家庭,自由漫游和自由养的家猫之间的毒性因素的差异.
探索与城市猫的肠道微生物组相关的潜在公共卫生影响.

主要方法:

从城市猫的三个组收集了便样本:家庭 (D),自由漫游 (FR) 和自由养的家庭 (FRD).
16S rRNA基因测序用于肠道微生物群的分类概况.
全基因组射击枪测序用于功能概况,包括识别抗生素耐药性基因 (ARG) 和毒性因子 (VF).

主要成果:

与家庭 (D) 组相比,自由养的家庭 (FRD) 组表现出最高的微生物多样性和更广泛的微生物类分布.
FRD猫拥有最独特的微生物种群和890个已识别的抗生素耐药性基因 (ARG) 的更多样化的特征.
FRD猫表现出独特的代谢途径和更高的毒性因子 (VF),以及潜在益生菌的识别.

结论:

猫的城市化和生活方式显著影响它们的肠道微生物群组成和功能潜力.
这些发现突出了由于FRD猫的各种ARG和VF引起的公共卫生问题,对动物和人类健康构成风险.
需要有针对性的监测和管理策略,强调了解城市猫咪微生物组对于公共卫生干预和猫咪福祉的重要性.

关键词:

抗生素耐药性基因是抗生素耐药性的基因.我们的肠道微生物组.有潜在的益生菌益生菌.城市环境城市环境毒性因素是毒性的因素.

更多相关视频

Establishment and Characterization of UTI and CAUTI in a Mouse Model

Establishment and Characterization of UTI and CAUTI in a Mouse Model

Published on: June 23, 2015

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

相关概念视频

Development of Antibiotic Resistance

Development of Antibiotic Resistance

Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...

Urine Studies II: Urine Culture and Sensitivity Test

Urine Studies II: Urine Culture and Sensitivity Test

A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...

Antimicrobial Effectiveness

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...

Microorganisms in Medicine and Therapeutics

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.