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猫的两个前运动区域 (6aα和6aγ) 在视觉引导的运动过程中参与了运动准备和执行
Nicolas Fortier-Lebel1, Toshi Nakajima2, Trevor Drew1
1Département de Neurosciences, Centre Interdisciplinaire de Recherche sur le Cerveau et l'Apprentissage (CIRCA), Université de Montréal, Pavillon Paul-G. Desmarais, C.P. 6128, Succursale Centre-ville, Montréal, Québec H3C 3J7, Canada.
Cerebral cortex (New York, N.Y. : 1991)
|August 1, 2025
概括
猫周十字皮层 (区域6aα和6aγ) 中的神经元有助于控制视觉引导的运动. 这些大脑区域参与规划和执行跨越障碍物时的步态调整.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 机车运动 机车运动
背景情况:
- 十字状皮质在运动控制中起作用.
- 了解其对视觉引导运动的具体贡献至关重要.
研究的目的:
- 在视觉引导的移动过程中,研究猫周十字皮层中6aα和6aγ区域的功能.
- 识别与障碍谈判有关的神经元活动模式.
主要方法:
- 单个单元活动记录来自猫周十字皮层的V层.
- 猫被训练在一个移动的皮带上跨越障碍物.
- 逆行标志物注射被用来绘制皮质投射的地图.
主要成果:
- 在两个区域6aα (53%) 和6aγ (25%) 的神经元群体在跨越障碍物时显示出改变的活动.
- 一些神经元对肢体的ipsilateral或contralateral步骤做出了特定的反应,而另一些神经元则无论肢体顺序如何都做出了反应.
- 观察到来自主运动皮层 (区域4γ) 和后壁皮层 (区域5) 的不同投影.
结论:
- 区域6aα和6aγ有助于规划和执行视觉引导步行修改.
- 区域4γ内的特定子区域的项目到6aα (近距离控制) 和6aγ (远程控制).
- 这些发现阐明了适应性运动的基础的神经电路.
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