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Updated: Sep 13, 2025

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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Published on: April 17, 2013

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布拉基瑞和IGF1R:在儿科甲状腺结节病理学中潜在的对立作用

Ayelen Martin1, María Celia Fernandez1, Sofía Miraglia1

  • 1Centro de Investigaciones Endocrinológicas Dr. César Bergadá (CEDIE), Fundación de Endocrinología Infantil (FEI), División de Endocrinología, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Hospital de Niños Ricardo Gutiérrez, Gallo 1330, Buenos Aires, C1425EFD, Argentina.

Journal of endocrinological investigation
|August 1, 2025
PubMed
概括

勃拉基瑞 (Brachy) 通过驱动上皮细胞转换为介质细胞转换 (EMT) 来促进儿童的侵袭性甲状腺癌,而类似胰岛素的生长因子受体1型 (IGF1R) 抑制瘤生长,这表明甲状腺瘤发生中的作用相反.

关键词:
布拉基尤里 (Brachyury) 是一个名为布拉基尤里 (Brachyury) 的机构.皮质到介质细胞的转变 (EMT)在IGF1R中,IGF1R是指IGF1R.儿童甲状腺癌的治疗方法

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